Book Luxury Vacation Rentals in South Carolina

Award-winning homes from £98

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Home spotlights in South Carolina

Oyster & Pearl

Oyster & Pearl

  • 8 guests

  • 3 bedrooms

Hilton Head Island, Beaufort County

Part of Sea Pines Plantation, where it all started for holiday rentals on beautiful Hilton Head Island, this fully renovated home is the perfect place to switch off and relax. Just a short walk from the beach, and with all the gated community's excellent amenities on hand, it's a peaceful and private getaway surrounded by pretty gardens and mature trees.

Scouting For Girls

Scouting For Girls

  • 4 guests

  • 1 bedrooms

North Historic District, Savannah

Sat right in the heart of Savannah's Historic District, the building in which this apartment is no youngster itself. Built back in 1860, it has served multiple purposes, but today it's a setting for a wonderful stay in this Georgian city.

Braves & Cardinals

Braves & Cardinals

  • 6 guests

  • 2 bedrooms

North Historic District, Savannah

Rather aptly for an apartment situated in Savannah's Historic District, the interior design of this home embraces weathered materials to create a rugged, lived-in effect. In the long open-living space, this comes in the form of exposed brickwork and steel beams, as well as the wooden floorboards underneath your feet.

Coastal Bliss Cottage

Coastal Bliss Cottage

  • 10 guests

  • 4 bedrooms

Isle of Palms, Charleston County

The Commodore is nestled in a charming street just off the Isle of Palms Beach. Featuring touches of Victorian design, a fully renovated interior, and four bedrooms, this home is the perfect spot to gather your family and friends for a relaxing trip to the beach.


We selected the top 3% holiday homes in South Carolina Vacation Rentals

Explore the 81 most perfect homes in our collection

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Most popular homes in South Carolina

Suburban Haven

Suburban Haven

  • 5 guests

  • 2 bedrooms

North Charleston, Charleston County

Damn Fine Coffee

Damn Fine Coffee

  • 11 guests

  • 5 bedrooms

North Charleston, Charleston County

Savannah Song

Savannah Song

  • 2 guests

  • 1 bedrooms

North Historic District, Savannah

The Forest City

The Forest City

  • 10 guests

  • 3 bedrooms

North Historic District, Savannah

Fuzzy Velvet

Fuzzy Velvet

  • 6 guests

  • 2 bedrooms

North Historic District, Savannah

Gonna Eat a Lot of Peaches

Gonna Eat a Lot of Peaches

  • 4 guests

  • 1 bedrooms

North Historic District, Savannah

Square City

Square City

  • 2 guests

  • 1 bedrooms

North Historic District, Savannah

Double Trouble

Double Trouble

  • 15 guests

  • 5 bedrooms

Hilton Head Island, Beaufort County

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Frequently asked questions

Take a look at our collection of luxury Vacation Rentals in South Carolina, United States. All of the homes you'll find on Plum Guide come fully furnished with all linen, the best-equipped kitchens, and essential bathroom toiletries included. Each home is systematically reviewed before becoming part of our collection, so you can book your stay with total confidence. And if you require any assistance in finding the perfect South Carolina Vacation Rentals for you, get in touch with our team of friendly experts, on hand to help with whatever you need.

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