Book Luxury Monthly Rentals in Santo Spirito

We selected the 47 homes worth renting in this location

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Home spotlights in Santo Spirito

A Rare Flower

A Rare Flower

  • 7 guests

  • 3 bedrooms

Santo Spirito, Florence

Moments from Ponte Vecchio, this apartment places you in the heart of historic Florence. It’s also just a short walk from the iconic Palazzo Pitti, while restaurants, galleries and artisanal shops can all be found within easy reach.

Arno View

Arno View

  • 6 guests

  • 2 bedrooms

Santo Spirito, Florence

This apartment in Florence boasts amazing views of the city and the Arno River. Housed in a 14th-century building, this elegant home, furnished with works by renowned local artists, offers a blend of historical charm and modern sophistication.

A Touch of Grace

A Touch of Grace

  • 5 guests

  • 2 bedrooms

Santo Spirito, Florence

It’s rare to find a garden apartment in the centre of Florence, especially one that only shares its plant-filled courtyard with one other home. Guests here have access to a big courtyard garden, furnished for evening drinks or meals outside and with a solarium should the weather turn.

Palazzo Pitti Retreat

Palazzo Pitti Retreat

  • 4 guests

  • 2 bedrooms

Santo Spirito, Florence

In the heart of Florence's trendy Oltrarno neighbourhood, this charming apartment is ideal for friends and families. Located on the top floor, both bedrooms have their own en-suites and there's a small balcony with space to stand out and enjoy the fresh air.


We selected the top 3% holiday homes in Santo Spirito Monthly Rentals

Explore the 47 most perfect homes in our collection

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Most popular homes in Santo Spirito

Terracotta & White Wood

Terracotta & White Wood

  • 6 guests

  • 3 bedrooms

Santo Spirito, Florence

Snowball

Snowball

  • 4 guests

  • 1 bedrooms

District 1, Florence

Florence Jewel

Florence Jewel

  • 4 guests

  • 2 bedrooms

Santo Spirito, Florence

Focal Length

Focal Length

  • 6 guests

  • 3 bedrooms

Santo Spirito, Florence

Divine & Delightful

Divine & Delightful

  • 4 guests

  • 2 bedrooms

Santo Spirito, Florence

Palazzo Paradiso

Palazzo Paradiso

  • 4 guests

  • 1 bedrooms

Santo Spirito, Florence

Pitti Pad

Pitti Pad

  • 8 guests

  • 4 bedrooms

Santo Spirito, Florence

Between the Bridges

Between the Bridges

  • 6 guests

  • 3 bedrooms

San Giovanni, Florence

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Check upcoming rates & availability for Santo Spirito Monthly Rentals


Frequently asked questions

Discover the ultimate collection of luxury Monthly Rentals in Santo Spirito, Florence, Tuscany, Italy, and say goodbye to all your travel troubles. Here at Plum Guide, it is our promise that each and every home in our range is in the top 3% of homes in its location, so there is no doubting the consistent quality we are able to offer. Secure your extended or short stay today and enjoy the trip of a lifetime in your fully furnished home, with every property on our site including all linens, essential bathroom toiletries, and a perfectly-equipped kitchen. Our meticulous home critics test everything from Wifi speed to a home's design, so you really can trust our judgement. Rent your perfect Santo Spirito Monthly Apartment today with the help of our team of experts, on standby 24/7 to assist you with absolutely anything.

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