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Rent Luxury Self-Catering Apartments in Santo Spirito

We selected the 47 homes worth renting in this location

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Who's coming along?

Adults

Age 13+

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Children

Age 1 to 12

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Pets

An extra fee may apply

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Home spotlights in Santo Spirito

Argonaut

Argonaut

  • 7 guests

  • 3 bedrooms

District 1, Florence

Argonaut is all about the view. It looks directly down onto the Arno and the Ponte Vecchio – one of Florence’s iconic structures.

From Firenze

From Firenze

  • 4 guests

  • 1 bedrooms

Santo Spirito, Florence

This wonderful apartment can be found right at the heart of beautiful Florence. It’s a bright and welcoming space, the perfect home from home for couples or a family hoping to experience authentic Firenze.

Jacopo

Jacopo

  • 8 guests

  • 3 bedrooms

Santo Spirito, Florence

Elegance meets comfort in this bright apartment located just across from Florence’s historic Ponte Vecchio. From its parquet flooring to its detailed wall panelling and contemporary furnishings, this home oozes subtle sophistication at every turn.

Palace on the Piazza

Palace on the Piazza

  • 7 guests

  • 4 bedrooms

San Frediano, Florence

How often do you get the chance to stay in a palace? On a darling little piazza?


We selected the top 3% holiday homes in Santo Spirito Self-Catering Apartments

Explore the 47 most perfect homes in our collection

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Most popular homes in Santo Spirito

Palazzo Paradiso

Palazzo Paradiso

  • 4 guests

  • 1 bedrooms

Santo Spirito, Florence

The Lights of Florence

The Lights of Florence

  • 5 guests

  • 3 bedrooms

San Giovanni, Florence

Student of Art

Student of Art

  • 6 guests

  • 3 bedrooms

San Frediano, Florence

The Modern Floret

The Modern Floret

  • 6 guests

  • 2 bedrooms

San Frediano, Florence

Fabulous In Florence

Fabulous In Florence

  • 7 guests

  • 3 bedrooms

San Frediano, Florence

The Basilica's Bell

The Basilica's Bell

  • 8 guests

  • 3 bedrooms

Santo Spirito, Florence

Aria to a Bird

Aria to a Bird

  • 2 guests

  • 1 bedrooms

Santo Spirito, Florence

Maggio Romance

Maggio Romance

  • 2 guests

  • 1 bedrooms

Santo Spirito, Florence

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Frequently asked questions

Book luxury Self-Catering Apartments in Santo Spirito, Florence, Tuscany, Italy, and enjoy a memorable stay for all the right reasons. We leave no stone unturned in our pursuit of the most remarkable homes, vetting everything from shower pressure to design aesthetic. Every home in our collection of luxury Santo Spirito Self-Catering Rentals comes fully furnished with a well-equipped kitchen, all linens, and essential bathroom toiletries included. And should you need any help in finding the perfect home, our friendly experts are always on hand to help.

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