Rent Luxury Self-Catering Apartments in Santo Spirito

We selected the 43 homes worth renting in this location

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Home spotlights in Santo Spirito

Cosmic Chord

Cosmic Chord

  • 2 guests

  • 1 bedrooms

Santo Spirito, Florence

This Angiolieri 12th-century tower house is located in Firenze's Oltrarno neighbourhood and offers Arno River views (you’ll need to be prepared to climb the 82 steps to reach it). Whether you’ve come here to experience Florence’s Gothic and Renaissance architecture, famous cuisine, or world-renowned art galleries, you’ll find this charming apartment in this historic building has the perfect local ambience and location.

Tresillo

Tresillo

  • 4 guests

  • 2 bedrooms

Santo Spirito, Florence

Tresillo is located on one of Florence's most characterful streets, right in the heart of the city – Ponte Vecchio is just a four minute walk away. Though the interior of the home is fairly pared back, we liked the balance of the modern design with the home's original features.

Arno View

Arno View

  • 6 guests

  • 3 bedrooms

Santo Spirito, Florence

This apartment in Florence boasts amazing views of the city and the Arno River. Housed in a 14th-century building, this elegant home, furnished with works by renowned local artists, offers a blend of historical charm and modern sophistication.

Jacopo

Jacopo

  • 8 guests

  • 3 bedrooms

Santo Spirito, Florence

Elegance meets comfort in this bright apartment located just across from Florence’s historic Ponte Vecchio. From its parquet flooring to its detailed wall panelling and contemporary furnishings, this home oozes subtle sophistication at every turn.


We selected the top 3% holiday homes in Santo Spirito Self-Catering Apartments

Explore the 43 most perfect homes in our collection

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Most popular homes in Santo Spirito

Power of Presence

Power of Presence

  • 6 guests

  • 3 bedrooms

Santo Spirito, Florence

Alberata Selva

Alberata Selva

  • 6 guests

  • 3 bedrooms

Santo Spirito, Florence

Astride the Arno

Astride the Arno

  • 4 guests

  • 2 bedrooms

San Giovanni, Florence

Argonaut

Argonaut

  • 7 guests

  • 3 bedrooms

District 1, Florence

The Basilica's Bell

The Basilica's Bell

  • 8 guests

  • 3 bedrooms

Santo Spirito, Florence

Florence Jewel

Florence Jewel

  • 4 guests

  • 2 bedrooms

Santo Spirito, Florence

Palazzo Pitti Retreat

Palazzo Pitti Retreat

  • 4 guests

  • 2 bedrooms

Santo Spirito, Florence

A Rare Flower

A Rare Flower

  • 7 guests

  • 3 bedrooms

Santo Spirito, Florence

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Frequently asked questions

Book luxury Self-Catering Apartments in Santo Spirito, Florence, Tuscany, Italy, and enjoy a memorable stay for all the right reasons. We leave no stone unturned in our pursuit of the most remarkable homes, vetting everything from shower pressure to design aesthetic. Every home in our collection of luxury Santo Spirito Self-Catering Rentals comes fully furnished with a well-equipped kitchen, all linens, and essential bathroom toiletries included. And should you need any help in finding the perfect home, our friendly experts are always on hand to help.

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