Book Luxury Vacation Rentals in Santo Spirito

Award-winning homes from £98

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Home spotlights in Santo Spirito

Aria to a Bird

Aria to a Bird

  • 2 guests

  • 1 bedrooms

Santo Spirito, Florence

Take things easy on one of two gorgeous balconies belonging to this dream of an apartment a short walk from central Florence. With views across the rooftops to the green hills, it's just about 50 metres from Ponte Viejo and Piazza Pitti.

Maggio Romance

Maggio Romance

  • 2 guests

  • 1 bedrooms

Santo Spirito, Florence

Couples seeking a rosy getaway in the romantic city of Florence – this is the home for you. Sitting in a city-centre building dating back to 1470, the elegant apartment boasts 180-degree views of the historic city.

Pitti Pad

Pitti Pad

  • 8 guests

  • 4 bedrooms

Santo Spirito, Florence

If you're looking for a central Florentine home that oozes Italian charm, this is it. And as a bonus, it boasts uninterrupted views of the famous Pitti Palace, sitting directly across from the magnificent structure.

What a Pitti

What a Pitti

  • 4 guests

  • 2 bedrooms

Santo Spirito, Florence

This home's location is the epitome of Renaissance grandeur. You'll find it perched in Pitti Square, just steps from the vast Renaissance marvel of the Pitti Palace, where you'll find an array of art galleries and museums.


We selected the top 3% holiday homes in Santo Spirito Vacation Rentals

Explore the 43 most perfect homes in our collection

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Most popular homes in Santo Spirito

Fabulous In Florence

Fabulous In Florence

  • 7 guests

  • 3 bedrooms

San Frediano, Florence

Mars & Venus

Mars & Venus

  • 3 guests

  • 1 bedrooms

Santo Spirito, Florence

Palazzo Paradiso

Palazzo Paradiso

  • 4 guests

  • 1 bedrooms

Santo Spirito, Florence

Jacopo

Jacopo

  • 8 guests

  • 3 bedrooms

Santo Spirito, Florence

The Raffaella Rose

The Raffaella Rose

  • 3 guests

  • 1 bedrooms

San Frediano, Florence

Florence Jewel

Florence Jewel

  • 4 guests

  • 2 bedrooms

Santo Spirito, Florence

Arno View

Arno View

  • 6 guests

  • 3 bedrooms

Santo Spirito, Florence

Cocoa & Lime

Cocoa & Lime

  • 5 guests

  • 3 bedrooms

San Frediano, Florence

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Frequently asked questions

Take a look at our collection of luxury Vacation Rentals in Santo Spirito, Florence, Tuscany, Italy. All of the homes you'll find on Plum Guide come fully furnished with all linen, the best-equipped kitchens, and essential bathroom toiletries included. Each home is systematically reviewed before becoming part of our collection, so you can book your stay with total confidence. And if you require any assistance in finding the perfect Santo Spirito Vacation Rentals for you, get in touch with our team of friendly experts, on hand to help with whatever you need.

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